Scientists reveal how brain imaging could identify people with Parkinson’s who might benefit most from a drug already used in ADHD — atomoxetine. The drug looks to improve cognition in Parkinson’s.

Researchers funded by Parkinson’s UK at the University of Cambridge provide further evidence that a drug used for ADHD might be beneficial for people with Parkinson’s who experience changes in cognition — the way they think and process actions. Their latest research shows the power of using brain scans to identify who might be most likely to benefit from the potential treatment.

Parkinson’s is not just a condition that affects movement, it has many hidden symptoms. Motor symptoms are largely caused by a reduction in levels of the vital brain chemical dopamine and most of the current medication works to…

Parkinson’s UK has teamed up with the biotech company — Clexio Biosciences Ltd. — “Clexio” — to help understand more about sleep problems in Parkinson’s.

Photo by Quin Stevenson on Unsplash

Sleep is fundamental. It’s often described as a way to let the body and mind recharge. There’s even evidence that sleep allows important repair and waste removal processes to happen inside our cells to ensure they can function properly. So it’s unsurprising that for those who experience difficulties sleeping, this can have a huge impact on their daily activities.

Parkinson’s has many symptoms, ranging from the more common and well recognised movement symptoms, such as…

Researchers are looking for 600 people with Parkinson’s to further investigate a treatment that has shown promise in reducing falls.

People with Parkinson’s often have trouble with balance and walking, which can result in falls. Falls affect 60% of people with Parkinson’s every year and can result in injuries, loss of confidence and anxiety. People living with the condition have told us that this should be a top research priority, as currently there are limited treatment options.

Researchers are currently investigating a treatment to reduce falls in people with Parkinson’s. The phase 3 trial is underway at 26 UK sites and is looking for people to take part.

In this blog post, we explain why this treatment looks promising and…

The coronavirus pandemic has highlighted the vital role of scientific research. In this blog we draw parallels between the science of the pandemic and Parkinson’s.

Photo by Daniel Schludi on Unsplash

The coronavirus pandemic has impacted people’s lives globally and with it has brought scientific discovery and discussions to the forefront of our minds. We have been inundated with information and updates, among this being scientific terms and processes for finding hopeful new treatments and prevention strategies. The foundation of these ideas and processes are not new, but the speed and urgency of the global response to developing, testing and approving a vaccine has been unprecedented.

During this challenging time Parkinson’s UK have been, and continue to be, dedicated to offering support to those living with Parkinson’s. …

The Parkinson’s UK Brain Bank is evolving — using technology to help piece together the mysteries of Parkinson’s deep within the brain.

Research into Parkinson’s has come a long way in the past couple of decades and is primed to deliver better treatments to improve symptoms and find a way to slow or stop Parkinson’s. But there are still pieces of the puzzle to uncover to help understand what’s happening inside the brains of those who have Parkinson’s compared to those who don’t. The Parkinson’s UK Brain Bank has a vital role to play in this quest for knowledge.

Technology also has an important role in accelerating research discoveries. Not only is it helping to improve the way we measure the condition…

Researchers show changes in vision could predict the development of thinking and memory problems in people with Parkinson’s.

Photo by David Travis on Unsplash

You may have heard the saying, ‘eyes are the windows to the soul’, but could they also be a ‘window’ to the brain. New research has shown that vision tests in people with Parkinson’s could help predict those at higher risk of thinking and memory problems.

Parkinson’s is a complex condition that has a wide range of symptoms, which can vary from one person to the next. One of the biggest challenges is predicting how the condition will progress in different people. If we could spot warning signs of cognitive changes early, then we’d be able to provide better treatment…

We met with Dr Dayne Beccano-Kelly to find out how he is accelerating the search for better treatments for Parkinson’s and dedicated to improving diversity in research.

Parkinson’s is a hugely variable condition where symptoms can be very different from one person to the next, making it complex to research. We’ve come on leaps and bounds, continually building on our understanding of Parkinson’s, and progress is being made in the development of better treatments. However, what has been limited and largely missing in research to date is understanding the role of ethnicity, with regard to the presentation, progression, symptom management and treatment of the condition.

You can read more about research into ethnicity and Parkinson’s and its limitations in a previous blog post.

We met with Dr…

Balance and falls are a major concern for people with Parkinson’s. Find out how new research aims to address this through the use of an easy to use handheld device.

The brain cells that are affected by Parkinson’s have a vital job to do. They release important chemicals that tell the body how to function. You may have heard of dopamine before, but one of the other chemicals released by these brain cells is called acetylcholine.

We know that acetylcholine is involved in memory, thinking and walking. And researchers believe that changes in acetylcholine levels, caused by the gradual loss of brain cells, may contribute to why people with Parkinson’s are at increased risk of falling.

Balance is such a huge issue that, when over 1000 people with Parkinson’s, their…

It’s more than just drugs that are being investigated to find better treatments for Parkinson's. We take a look at some of the devices that are currently in clinical trials.

What if the next exciting treatment for Parkinson’s isn’t a new pill? What if a headset or handheld device could control specific symptoms of Parkinson’s or even help to slow its progression?

Technology has a growing role to play in the monitoring of our health and wellbeing in the 21st century. Health data is at our fingertips with wearables such as watches that monitor heart rate, tech you can take home to encourage exercise and apps that help people to manage their mood. So it is not surprising that cutting edge technology is being harnessed in medical research.

In Parkinson’s…

Focused ultrasound has potential as a non-invasive treatment for Parkinson’s. We chat to Professor Wladyslaw Gedroyc, Consultant Radiologist at Imperial College, to find out the latest.

Photo by Miikka Luotio on Unsplash

Most people with Parkinson’s will use medication to help control their symptoms, but for some, over time, medications alone may no longer be enough to control symptoms. This is when specialists may look towards surgical options. Currently deep brain stimulation (DBS) offers the main surgical way to control movement symptoms of Parkinson’s.

This type of surgery involves inserting fine wires into the brain to be controlled by a pulse generator (a device like a heart pacemaker) that is placed under the skin around the chest or stomach area. When the pulse generator is switched on, the electrodes deliver high frequency…

Dr Katherine Fletcher

Research Communications Officer

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